There have been many celebrated scientists in fiction. A disproportionate number of these have been depicted as mad, working on outlandish experiments to change the world and often nearly destroying it in the process. They usually end up destroying themselves. I often wonder if it is because of these fictional caricatures that people regard scientists and the science they produce with suspicion. However, the real reason is almost certainly because of their inability to communicate properly with the public.
I have spent most of my working life as a biological scientist while writing fiction in my spare time. Up until a few years ago I have been reluctant to publish any fictional science. I know how much effort goes into researching real science and getting it to work. Fictionalising it, by making it up goes against the grain. But what in the past has been regarded simply as science fiction is often now becoming science fact and so this form of fiction is now a real force in driving fact.
My novel Magic Bullets at http://peatmore.com/magicbullets.htm